The Hematology Department led by experts dedicates themselves to patients with problems in their blood. Such problems can be Congenital (from birth) diseases like Thalassemia and Hemophilia or other issues like Leukemia and forms of Anemia (like Sickle Cell).
Common Blood Related Problems Include
- Thalassemia – a genetic problem related to an individual’s blood.
- Bone marrow failure syndromes such as aplastic anaemia.
- Blood cancers such as Leukemia, Lymphomas (cancer affecting lymph nodes) and Multiple Myeloma.
- Bleeding disorders like hemophilia and platelet related disorders.
Treatment Options for Blood Disorders
First, the defective bone marrow that has caused the disease, like leukaemia, must be killed/destroyed to get rid of the damaged cells. This is done with radiotherapy or large doses of chemotherapy (drugs).
Getting New Cells From Relatives
The next step is the transplant. Bone Marrow Transplants come from a donor, often a relative of the patient. A minor operation retrieves healthy cells from inside the donor’s bones to transfer to the sick person. This is an allogeneic transplant. The donor cells are given to the patient through a needle in the arm – just like a blood transfusion.
Getting New Cells From The Patient
Some transplants take the patient’s own cells – this is an autologous transplant. This is done if no relative’s with blood matches with the patient’s blood. After chemotherapy, in remission, the healthy cells start growing. Growth factor is given to help the cells multiply so there are enough for the transplant. This is a bit like donating blood but the blood goes into a cell separation machine. Here the stem cells separated but the rest of the cells are injected back to the patient. It just takes 2-4 hours. Autologous transplants are done mainly for patients with multiple myeloma. It mobilizes peripheral blood stem cells.
Investigations & Procedures Done At Hematology Unit
- Bone Marrow Transplantation, click here for more information
- Stress Cytogenetics
- Expansion of Cells
Specific Blood Problems & Specific Treatments
Haemophilia is a genetic disease more common in boys. A type of gene hampers blood’s clotting function, and the suffering individual bleeds copiously, even from minor injuries. Bleeding also happens in muscles and joints e.g. knees and elbows. This causes pain and prevents patients from using their arms and legs properly.
Treatment: Clotting Factors can be injected into a patient to stop the problem, but factors are expensive and difficult to afford in India. Normally, special care is given for patients with Haemophilia, under the strict supervision of Hematologists. They also work with the orthopaedic surgeons, physical medicine, and rehabilitation specialists, for regaining muscle and joints usage.
Thalassemia is a congenital genetic disease. A child is born with a gene that impedes proper haemoglobin development and as such, problems start at an early age.
Treatment: At Ruby Hall Clinic, BMT is used to treat Thalassemia and 60 transplants have been done so far with a success rate of 75% even though most of the patients were in Class II or III.
Molecular Genetics and Antenatal Diagnosis
For most patients/carriers with Thalassemia a test is done that finds the gene causing the problem. A carrier is someone who has the abnormal gene but it does not cause any problems. The test is done by looking at the patient’s DNA. The department can also give an antenatal diagnosis. This means that during the 8th week of pregnant a family can test to see if the baby has the abnormal gene that would give the child Thalassemia.
Panel of Doctors
|Name||OPD Day||OPD Timings|
|Dr. Vijay Ramanan||Tue, Wed, Thu||9.30 AM – 11 AM|
|Dr. Abhijit Baheti||Mon to Sat||2 PM – 5 PM|